Fifteen years ago, the World Health Organisation’s Framework Convention on Tobacco Control (FCTC) came into force, the first global compact to systematically address the burden of tobacco related health problems. [...]

The objective of the special issue in Drugs and Alcohol Today [2] and of this “15 Years Conference” organised in its wake is to take stock of the current global tobacco control landscape, highlight the challenges in the development and delivery of effective harm reduction tools globally, and discuss the opportunities to accelerate the decline of risky tobacco use globally- without leaving anyone behind.