Nicotine Science and Policy

By Harry Shapiro Sept. 11, 2025

Harry’s blog 129: Prohibition: the lessons we never learn

Australia’s unnecessary nicotine war lights up,

As reported on the website of ALIVE, the Australian vaping advocacy movement, “Australia's ongoing battle against tobacco has led to some of the strictest regulations in the world, particularly concerning vaping and cigarette pricing. While the government has framed these policies as necessary for public health, the unintended consequences have sparked a growing crisis.”

Recent GFN-TV Interviews

December 04, 2025 by daily-pouch.com

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The Problems With ASH Scotland’s Midwife’s Guide to NRT

ASH Scotland released a guide for midwives on addressing nicotine use during pregnancy, causing confusion rather than clarity. The guide implies medicinal nicotine replacement therapy (NRT) is far safer than commercial products, despite both containing the same compound. Differences lie in purity, dose, and regulation, but evidence doesn't conclusively support medicinal NRT being "far safer." Caution is advised for pregnant individuals until further research clarifies the risks.


11.80% of the adult population are current smokers. There are approximately 6.7 million current smokers in United Kingdom 13.60% of men are current smokers but only 10.10% of women.
SOURCE: GSTHR

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December 04, 2025 by spotify.com

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Clive Bates: when tobacco control turns against public health

The text discusses an episode of "Aclaremos las cosas" with Clive Bates on tobacco control policy. The conversation criticizes the WHO Framework Convention for being bureaucratic and anti-industry instead of harm reduction-focused. It highlights issues like Article 5.3, excluding dissenting voices, organized crime impacts of bans, and missed opportunities for harm reduction. The episode calls attention to philanthropic foundation influence on global narratives about nicotine.



December 04, 2025 by clearingtheair.eu

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EXCLUSIVE: “Rethink the status quo” – two former WHO directors call for radical overhaul of global nicotine policy

Former WHO Directors Derek Yach and Tikki Pang advocate a radical overhaul of the WHO's tobacco control treaty for harm reduction. They emphasize the need for courage from governments, industry, and civil society to prioritize public health over old beliefs. Highlighting the importance of informing healthcare professionals, they urge scientific societies and journals to support harm reduction strategies. The authors stress the urgency for low-income countries to adopt these measures to prevent long-term health and economic burdens. Contrasting progress in developed and developing nations, they argue for embracing safer alternatives to reduce smoking-related harm. Despite past mistrust of tobacco companies, they call for a pragmatic shift towards harm reduction to save lives.



December 04, 2025 by radio.cz

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Cotton-candy countdown: new vape rules target rising youth addiction

A new Czech law bans candy-flavored electronic cigarettes, giving stores seven months to sell existing stocks. The law aims to protect youth as over a quarter of young users prefer candy flavors. Experts warn that nicotine in e-cigarettes harms adolescent brain development, leading to addiction and behavioral issues. The ban targets flavors attracting minors, while adult users can still access other options. The move follows concerns that e-cigarettes increase smoking rates, especially among minors. Critics suggest enforcing existing laws against selling any cigarettes to minors. Addiction specialist Adam Kulhánek supports the ban on candy flavors to safeguard children's health.


26.30% of the adult population are current smokers. There are approximately 2.4 million current smokers in Czech Republic 30.80% of men are current smokers but only 21.90% of women.
SOURCE: GSTHR

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December 04, 2025 by medicalxpress.com

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Brain enzyme that drives nicotine addiction and smoking dependence identified

Research reveals that astrocytes' enzyme, glutamine synthetase, plays a crucial role in nicotine addiction, influencing brain changes and addictive behavior. Led by Prof. Choe, the study found that astrocytes interact with neurons to regulate nicotine-dependent behavior. Nicotine exposure stimulates receptors on astrocytes, triggering a calcium surge and signaling pathways that enhance locomotor sensitization. By blocking specific interactions in rats' brains, researchers dampened locomotor sensitization, underscoring astrocytic signaling's significance in nicotine-induced brain changes. These findings suggest a new avenue for addiction research, emphasizing glia communication and potential therapeutic strategies for smoking cessation.


December 04, 2025 by prnewswire.com

Pusan National University Researchers Identify the Brain Enzyme That Drives Nicotine Addiction and Smoking Dependence

Researchers have found that astrocytes, overlooked glial cells in the brain, actively influence nic…


17.60% of the adult population are current smokers. There are approximately 8.1 million current smokers in South Korea 30.20% of men are current smokers but only 5.10% of women.
SOURCE: GSTHR

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December 04, 2025 by tobaccoreporter.com

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NZ Minister Grilled Over Oral Nicotine Plan

Associate Health Minister Casey Costello was questioned about the government's plan to permit oral nicotine products, despite denying ties to the tobacco industry. Costello emphasized harm reduction and safety precautions to prevent youth access. Labour's Dr. Ayesha Verrall cautioned against potential new addictions in youths, urging Costello to follow expert advice before introducing the products. Public health researcher Dr. Jude Ball highlighted the lack of evidence supporting oral nicotine products for smoking cessation and warned about tobacco companies promoting youth consumption. Costello is still reviewing recommendations on the matter.


December 03, 2025 by rnz.co.nz

Health select committee erupts into heated debate over roll out of oral tobacco and nicotine products

Associate Health Minister Casey Costello faced criticism over government plans to introduce oral to…


8.60% of the adult population are current smokers. There are approximately 364,000 current smokers in New Zealand.
SOURCE: GSTHR

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December 04, 2025 by cbc.ca

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Nicotine pouches glamourized on social media, little talk about risks for youth, study finds

Researchers at UBCO warn that TikTok videos glamorizing nicotine pouch use are shaping a trendy image, particularly among youth. Despite Health Canada authorizing these pouches for adult smoking cessation, they're off-limits for under-18s. Dr. Laura Struik's analysis of 250 videos, totaling nearly 2 million shares, highlights how users portray pouches as seamless with daily life. The videos fail to address potential health risks like gum recession and heart problems from prolonged use. Struik suggests involving young people in policy discussions about these products. Health Canada is enforcing regulations on approved pouch brands due to concerns about unauthorized sales to minors.


December 02, 2025 by medicalxpress.com

From cessation to celebration: Nicotine pouches go viral on TikTok

UBC Okanagan research by Dr. Struik warns of the misleading trendiness of oral nicotine pouches pro…


10.60% of the adult population are current smokers. There are approximately 3.5 million current smokers in Canada 13.10% of men are current smokers but only 8.10% of women.
SOURCE: GSTHR

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December 04, 2025 by swissinfo.ch

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World fights nicotine addiction but Switzerland continues to drag feet

Switzerland's failure to ratify the WHO Framework Convention on Tobacco Control despite hosting WHO's headquarters allows the tobacco industry to wield significant influence. Despite COP11 decisions to tackle issues like environmental pollution and deceptive industry claims, the tobacco lobby continues to impede global tobacco control efforts. Switzerland's strong ties between the tobacco industry and politicians hinder progress, with the country ranking poorly in the Global Tobacco Industry Interference Index. The tobacco industry's active presence in policymaking highlights the weaknesses in Swiss tobacco control legislation, as seen through the watering down of key regulations. This contributes to Switzerland's low ranking in tobacco control policy implementation compared to other European countries.


21.00% of the adult population are current smokers. There are approximately 1.6 million current smokers in Switzerland.
SOURCE: GSTHR

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December 03, 2025 by eureporter.co

Danish Presidency and European Commission push 'super tax' on heated tobacco as NGO influence overrides member state concerns

Denmark’s EU Presidency has proposed a sharp tax increase on heated tobacco products in a last-minute revision of the Tobacco Excise Directive, favoring NGO anti-tobacco demands while ignoring member states’ concerns The new draft, circulated on 28 November, introduces higher minimum taxes, changes product definitions, and sparks criticism for bypassing democratic scrutiny Critics argue the “super tax” undermines harm-reduction goals and reflects advocacy more than EU state consensus.


December 03, 2025 by worldvapersalliance.com

WVA condemns EU “super tax” proposal on heated tobacco

The World Vapers’ Alliance opposes the proposed EU tax hike on heated tobacco and harm-reduction pr…


15.60% of the adult population are current smokers. There are approximately 781,000 current smokers in Denmark.
SOURCE: GSTHR

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December 03, 2025 by ticotimes.net

Costa Rica Eyes Complete Vape Ban to Combat Rising Teen Use and Risks

Costa Rica's ruling party member proposes a bill to ban vapes completely, citing health risks, especially for youth. The bill includes outlawing import, sale, and use, as well as related activities like advertising and distribution. Law 25.309 would also establish a prohibited substances list and repeal a current law with a 20% tax on vaping products. The lawmaker emphasizes minors' easy access to vapes, health issues like lung damage, and industry tactics targeting young users. The proposal mirrors bans in other Latin American countries and faces concerns about potential black markets. The bill is pending further legislative review.


7.80% of the adult population are current smokers. There are approximately 323,000 current smokers in Costa Rica 11.80% of men are current smokers but only 4.00% of women.
SOURCE: GSTHR

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Blogs

Harry’s blog 129: Prohibition: the lessons we never learn

Australia’s unnecessary nicotine war lights up,

As reported on the website of ALIVE, the Australian vaping advocacy movement, “Australia's ongoing battle against tobacco has led to some of the strictest regulations in the world, particularly concerning vaping and cigarette pricing. While the government has framed these policies as necessary for public health, the unintended consequences have sparked a growing crisis.”

Harry’s blog 128: Behind the smoke and mirrors: the continuing challenge of tobacco harm reduction.

“If you assume that there is no hope, you guarantee there will be no hope”. Noam Chomsky

I recently returned from the 12th annual Global Forum on Nicotine (GFN) conference in Warsaw. My first visit was 2015 when I had just entered the tobacco harm reduction (THR) space after over thirty years spent with UK NGOs advocating for drug and HIV harm reduction – a space I still inhabit.

Harry’s blog 127: The truth is still out there.

A free self-guided introduction to tobacco harm reduction from K•A•C aims to raise awareness of the approach among a wider community of policymakers, researchers, health professionals – and adult smokers.