Adults who regularly used electronic nicotine delivery devices, or e-cigarettes, displayed worrisome changes in heart and blood vessel function and performed significantly worse on exercise stress testing than people who did not use any nicotine products, according to two separate analyses of preliminary research to be presented at the American Heart Association’s Scientific Sessions 2022. [...] Researchers from the Cardiac and LUng E-cig Smoking (CLUES) Study will present two abstracts that compared outcomes among people who vaped, those who smoked traditional, combustible cigarettes and people who reported not using any nicotine products.