No, Synthetic Opioid Cychlorphine Has Not Proved Narcan “Ineffective”
March 06, 2026 by filtermag.org
No, Synthetic Opioid Cychlorphine Has Not Proved Narcan “Ineffective”
A new synthetic opioid called cychlorphine is a cause for concern due to its potency and involvement in overdose deaths in the US and Canada. Despite reports of naloxone being ineffective against it, there is no concrete evidence to support this claim. The substance, mistakenly referred to as chlorphine, has been linked to fatalities, with warnings issued by forensic centers and health departments. However, naloxone's effectiveness in reversing cychlorphine overdoses remains uncertain. Misconceptions about naloxone's mechanism of action and the confusion between cychlorphine and chlorphine have caused confusion and heightened alarm regarding the drug's dangers.
