🍷 A common brain circuit for alcohol and nicotine
September 05, 2025 by techno-science.net
🍷 A common brain circuit for alcohol and nicotine
Nicotine and alcohol activate a brain circuit connecting reward and anxiety by triggering an inhibitory feedback loop between dopaminergic neurons. This mechanism explains why these substances reinforce consumption behavior while inducing anxiety. Researchers used optogenetics to block this loop and prevent anxious behavior. The study sheds light on the link between reward and negative emotions, providing insights into addiction and co-use of tobacco and alcohol.
