Nicotine Science and Policy

By Harry Shapiro July 10, 2026

Harry’s Blog 132: “Zyn! Went The Strings Of My Heart” (with apologies to Judy Garland)

FDA approval of 20 nicotine pouch products is another step forward for tobacco harm reduction

The FDA in the U.S. has granted marketing authorisation for Zyn nicotine pouch products (five variations on mint plus five other flavours in two different strengths).

In its letter to PMI (who own Zyn manufacturers Swedish Match), the FDA wrote:

Based on our review of your MRTPAs [Modified Risk Tobacco Applications] we determined that the proposed modified risk tobacco products, …as actually used by consumers would significantly reduce harm and the risk of tobacco-related disease to individual tobacco users and benefit the health of the population as a whole, taking into account both users of tobacco products and persons who do not currently use tobacco products. Therefore, we authorize marketing of the tobacco products as modified risk tobacco products with the following modified risk information – “Using ZYN instead of cigarettes puts you at a lower risk of mouth cancer, heart disease, lung cancer, stroke, emphysema and chronic bronchitis”.

July 03, 2026 by gfn.tv

THR Unfiltered #2 | How should we think about nicotine addiction?

Nicotine addiction should be understood with nuance, not moral panic. Dependence is real, but it should not be confused with the harms caused by burning tobacco. For people who smoke, moving to lower-risk nicotine products can reduce exposure to the toxicants responsible for most smoking-related disease. Better policy starts by separating addiction, risk and harm — and by helping people make safer choices.


World map

14.10% of the adult population are current smokers. There are approximately 39.8 million current smokers in United States 17.10% of men are current smokers but only 11.10% of women.
SOURCE: GSTHR




July 03, 2026 by worldvapersalliance.com

Kenya's Tobacco Control Bill Should Follow Science, Not Fear

Kenya’s tobacco control bill should be guided by science, not fear. Regulation must protect young people, but it should also recognise the difference between combustible cigarettes and lower-risk nicotine alternatives. If safer products are restricted too heavily, adult smokers may be left with fewer realistic options to quit. Evidence-based policy should reduce harm, preserve informed choice and keep alternatives within legal, regulated markets.


World map

6.40% of the adult population are current smokers. There are approximately 2.3 million current smokers in Kenya 12.10% of men are current smokers but only 0.90% of women.
SOURCE: GSTHR

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July 03, 2026 by planetofthevapes.co.uk

The ‘Donald Trump Of Fake Science’

Bad science becomes a public health problem when weak claims are repeated as certainty. In nicotine policy, flawed studies and exaggerated conclusions can distort risk perception, fuel moral panic and push regulation away from evidence. Vaping should be scrutinised, but criticism must be grounded in robust methods, fair comparisons and context on relative risk. Public health loses credibility when advocacy is dressed up as science.



July 03, 2026 by maldivesindependent.com

A WHO rate, unseen studies and a U-turn: Maldives makes cigarettes cheaper

The Maldives’ decision to make cigarettes cheaper raises serious questions about the consistency of tobacco policy. If public health advice is shaped by opaque studies and international pressure while lower-risk alternatives remain restricted, smokers may be left with the most harmful option made more affordable. Reducing harm requires transparent evidence, proportionate regulation and policies that distinguish between combustible tobacco and safer nicotine products. Public health should not protect cigarettes by default.


World map

28.80% of the adult population are current smokers. There are approximately 120,000 current smokers in Maldives 43.30% of men are current smokers but only 3.20% of women.
SOURCE: GSTHR

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July 03, 2026 by dailycaller.com

What The FDA’s Latest Ruling Could Mean For Future Of Nicotine Pouches

The FDA’s ruling on nicotine pouches is a major step towards honest relative-risk communication. By recognising that authorised smoke-free products can present lower risks than cigarettes, regulators are acknowledging what tobacco harm reduction has long argued: combustion is the central danger. Adult smokers need clear, accurate information about alternatives that may help them move away from cigarettes. Public health policy should make safer choices easier to understand, not harder to access.


July 02, 2026 by realclearscience.com

On Nicotine, FDA Embraces Science and Delivers a Public Health Victory

The FDA’s authorisation of modified risk claims for ZYN nicotine pouches marks a public health win …


World map

14.10% of the adult population are current smokers. There are approximately 39.8 million current smokers in United States 17.10% of men are current smokers but only 11.10% of women.
SOURCE: GSTHR


Blogs

Harry’s Blog 132: “Zyn! Went The Strings Of My Heart” (with apologies to Judy Garland)

FDA approval of 20 nicotine pouch products is another step forward for tobacco harm reduction

The FDA in the U.S. has granted marketing authorisation for Zyn nicotine pouch products (five variations on mint plus five other flavours in two different strengths).

In its letter to PMI (who own Zyn manufacturers Swedish Match), the FDA wrote:

Based on our review of your MRTPAs [Modified Risk Tobacco Applications] we determined that the proposed modified risk tobacco products, …as actually used by consumers would significantly reduce harm and the risk of tobacco-related disease to individual tobacco users and benefit the health of the population as a whole, taking into account both users of tobacco products and persons who do not currently use tobacco products. Therefore, we authorize marketing of the tobacco products as modified risk tobacco products with the following modified risk information – “Using ZYN instead of cigarettes puts you at a lower risk of mouth cancer, heart disease, lung cancer, stroke, emphysema and chronic bronchitis”.

Harry’s Blog 131: Hidden harms

New publications from K•A•C discuss the challenge of smoking in treatment services caring for those who are HIV positive or coping with drug problems.

Smoking rates among those who are HIV positive and those who use drugs (as well as those with mental health problems where there may well be overlap) are anything from two to four times higher than the general adult smoking rates of most developed countries. One study of those receiving opiate substitute treatment recorded a smoking prevalence rate of 85%. Why should this be?

Harry’s blog 130: Follow the science not the money

For the sake of public health, end virtue signalling about THR funding

I arrived into the world of tobacco harm reduction (THR) from drugs and HIV harm reduction in 2015. I was invited into KAC by two valued colleagues from my previous world who were perfectly up front (and have never hidden the fact) that the funding for the organisation came from the Foundation for a Smoke Free World which in turn was funded by Philip Morris International. And the reason that they were prepared to use this money to further the cause of THR was that no other prospective funders for a harm reduction project were interested. Nobody back in the day was excited by the fact that if you could separate nicotine use from combustion the relative risk was massively reduced and the potential health gains enormous.