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Studies on the chemical composition of e-cigarette liquids are raising concern that regulation is lagging behind the data.

The Yale Tobacco Center for Regulatory Science is a National Institute of Health and US Food and Drug Administration funded research group tasked with investigating the influence of flavours on tobacco addiction. Part of this work involves assessing the composition of e-cigarette liquids being sold to users. E-liquids contain mainly nicotine, flavourings and a solvent in which ingredients are dissolved.