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Even after decades of public health efforts to reduce tobacco use, it remains the leading preventable cause of disease and death in the United States and is a significant driver of healthcare costs. In fact, in 2018, 34 million US adults reported smoking cigarettes, and approximately 20% of US adults said they used some type of tobacco product. Smoking-related illnesses, deaths, and costs can be prevented by helping people quit using tobacco. But how do we do it?