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E-cigarette flavors can damage the cells that line your blood vessels and perhaps your heart health down the line, according to a new study of human cells in the lab.

The study, published Monday in the Journal of the American College of Cardiology, adds to growing evidence that the flavored "e-liquids" used in vapes can hinder human cells' ability to survive and function. The authors say these changes, some observed in the absence of nicotine, are known to play a role in heart disease.