As an internist who treats hundreds of recalcitrant smokers a year, I was desperate for useful quitting techniques. I finally found a successful approach. In most cases a nicotine patch during the day, combined with e-cigarettes when the urge for tobacco hits, works best. Vaping is less dangerous than cigarette smoking, but it isn’t harmless, and the long-term health effects aren’t yet known. The American Society of Clinical Oncology, American Association for Cancer Research and American Heart Association have all expressed concerns about e-cigarettes.