At the beginning of the 21st century the scientific and technological advancement forced
a change in the way of thinking about nicotine; it also enabled the harmfulness of various types
of nicotine delivery products to be analysed, which constitutes an essential step towards the
determination of the continuum of risk of tobacco products. The availability of products with
various levels of harmfulness enables one to take a complete set of actions towards smokers
which include both those aiming at complete smoking cessation [...]