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Separate studies suggest that the risks from smoking might vary between high-income (HICs), middle-income (MICs), and low-income (LICs) countries, but this has not yet been systematically examined within a single study using standardised approaches. We examined the variations in risks from smoking across different country income groups and some of their potential reasons. We analysed data from 134 909 participants from 21 countries followed up for a median of 11·3 years in the Prospective Urban Rural Epidemiology (PURE) cohort study; [...]

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The spread of SARS-CoV-2 and ongoing COVID-19 pandemic underscores the need for new treatments. Here we report that cannabidiol (CBD) inhibits infection of SARS-CoV-2 in cells and mice. CBD and its metabolite 7-OH-CBD, but not THC or other congeneric cannabinoids tested, potently block SARS-CoV-2 replication in lung epithelial cells. CBD acts after viral entry, inhibiting viral gene expression and reversing many effects of SARS-CoV-2 on host gene transcription. CBD inhibits SARS-CoV-2 replication in part by up-regulating the host IRE1α RNase endoplasmic reticulum (ER) stress response and interferon signaling pathways. [...]

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Billionaire philanthropist Michael Bloomberg is the man behind many of the organizations and initiatives dedicated to the destruction of vaping.

Arguably, he’s the single most important person to educate on vaping’s potential to save the lives of millions of smokers. But how to reach him?

Joining us today is Dr. John Oyston to discuss a charming new project to educate Mr. Bloomberg while wishing him a Happy 80th Birthday!

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A new study reveals low awareness among some Taiwanese electronic cigarette users they are vaping nicotine.

The online study, which received 1,608 valid samples from people aged 15 to 49, found that 5.5% are active vapers. The survey found 44.6% of them do not realize many vaping cartridges contain nicotine, according to the Health Promotion Administration (HPA).

According to an inspection conducted by the Food and Drug Administration, up to 90% of vaping products on the market were found to contain nicotine. For the nicotine-free ones, many still have methanol, ethanol, or other toxic substances, HPA said.

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Researchers of the University of Bologna carried out a study on murine models (mice) demonstrating that pre-natal exposure to nicotine and its by-products produces long-term effects on sleep and stress-response in some areas of the brain. [...] "The results of this study show how sleep in adults might be influcenced by events occurred in the early stages of life," explains Giovanna Zoccoli who coordinated the research and is a professor at the Department of Biomedical and Neuromotor Sciences of the University of Bologna. "According to our data, control over environmental factors during pregnancy is fundamental not only for women's health but also for the offspring's."

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Dr Sharon Cox has spoken to the Society for the Study of Addictions on a podcast about her trial looking at helping people experiencing homelessness to switch to vaping. [...] The monthly podcast summarises the latest news from across the addictions sector. A lot of Sharon’s recent work has been to deliver smoking cessation solutions to people experiencing homelessness. [...] “As well as knowing how smoking impacts health, we know that it impacts people’s mental health, it impacts their wellbeing, and it also has huge financial implications with up to a third of people’s low incomes going on their tobacco. [...]

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Chinese e-cigarette billionaire Chu Lam Yiu is under investigation from Chinese authorities, causing shares of her company, Hong Kong-listed Huabao International, to fall by over 65% on Monday.

Chu, who serves as chair and CEO, is currently under investigation for “suspected disciplinary violations” of an unclear nature, the fragrances and tobacco flavoring supplier announced on Monday. [...] Chu, 52, owns approximately 70% of Huabao International’s shares. Often dubbed “China’s vaping queen” for overseeing Huabao International’s entry into the e-cigarette market, Forbes estimates her net worth at $2.6 billion as of Monday’s close.

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The popularity of disposable vapes are growing which is causing serious environmental damage due to the single-use nature of the product.

Across Bournemouth, over 90 per cent of young vape users have admitted to taking up the habit over the last two years.

Andrej Kuttruf, CEO of vape company Evapo, now have over 40 shops across the UK, including Bournemouth, because of an increased demand.

He said: “Disposable vapes are a relatively new product category. They were very popular in the US, and now in the UK as well because they take away all the headaches of normal vaping, they resemble a normal cigarette, and they are much more convenient.

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MANILA — Doctors from various fields on Monday urged President Rodrigo Duterte to veto a controversial bill that they claim would ultimately "deregulate" the sale and consumption of vaporized nicotine and non-nicotine products or vapes. In a press conference organized by the Philippine College of Physicians (PCP), at least 5 doctors representing their medical societies voiced their opposition to the proposed Vaporized Nicotine and Non-Nicotine Regulation Act, recently approved by the bicameral conference committee. 

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E-cigarettes may benefit public health if they are effective for smoking cessation. Evidence suggests that the frequency of e-cigarette use is likely an important predicator of smoking cessation success, so we examined the associations between frequency of e-cigarette use and smoking reduction and cessation in an Australian population sample of past year adult smokers. [...] Daily, but not occasional, e-cigarette users were more likely to quit or reduce smoking cigarettes than Australian smokers who did not use e-cigarettes.

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Asa Salikupt, from the End Cigarette Smoke Thailand (ECST) network, said the network supports DES Minister Chaiwut Thanakamanusorn’s plan to legalise e-cigarettes and hopes the working group will be transparent, listen to public opinions and allow e-cigarette users to provide information. "We believe the legalisation of e-cigarettes will help Thailand achieve the goal of reducing cigarette smokers and protecting non-smokers from the danger of second-hand smoke,” he said. He also pointed out that the Excise Department can introduce an e-cigarette tax once it’s legalised.

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Expressing anguish over steep increase in the volume of sale of smuggled cigarettes in the state, Federation of All India Farmers Associations (FAIFA) has appealed to the state government to launch a crackdown on the sellers. The FAIFA said that illegal sale of unauthorised cigarettes is not only causing huge loss to the exchequer but also affecting the incomes of the tobacco farmers in AP.

[...] “Tobacco in AP generates enormous economic benefits in terms of agricultural employment, farm incomes, revenue generation and foreign exchange earnings. India is the world’s 2nd largest producer and exporter of tobacco [...]

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It’s National Non-Smoking Week in Canada, which falls on the third week of January and is dedicated to raising awareness of the dangers of smoking cigarettes. January 2022 is also the month that Health Canada had hoped it would be able to implement a ban on flavoured vaping products — a proposal that will discourage smokers from switching to less-harmful products. But perhaps that’s exactly the point. Nobody should be surprised that money and taxes has played a huge role in shaping the public health crusade to end smoking in Canada. [...]

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Detrás de la Nube (Behind the Cloud) is a documentary that seeks to show from the inside the efforts of different Latin American activists and experts to fight misinformation in the legislative bodies of their countries, provide reliable scientific information on the harm reduction approach to tobacco and nicotine, fight against tobacco lobbies and celebrate saving their lives by quitting smoking and opting for safer alternatives such as vaping.

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The US Food and Drug Administration recently announced its intention to pursue a federal ban on menthol cigarettes. This qualitative study assessed reactions to a potential menthol cigarette ban among people who smoke menthol cigarettes. Many participants thought menthol cigarettes carried more health risks than non-menthol cigarettes. Some participants said regulators wanted to ban menthol cigarettes because they appeal to youth. Others thought a ban would be good for public health because fewer people, particularly youth, would smoke. Several voiced skepticism about banning only menthol cigarettes rather than all cigarettes. [...]

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WASHINGTON — It’s been more than four months since the Food and Drug Administration (FDA) was supposed to decide which e-cigarette products can remain on the market, but the agency still hasn’t completed some of the reviews.

In response, several anti-tobacco groups sent a letter to the FDA urging it to take action on the outstanding premarket tobacco product applications (PMTAs) and pushed for the FDA to deny applications for flavored e-cigarette products.

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Amid a months-long wait for clarity on the future of vaping in the United States, people on all sides of the tobacco harm reduction debate are growing anxious.

On January 14, a collection of public health nonprofits and tobacco control groups [...] sent a letter to Mitch Zeller, the director of the Food and Drug Administration’s Center for Tobacco Products (CTP). The groups—many of which are funded by billionaire Michael Bloomberg and all of which want to clamp down on vaping—urged the agency to “expedite” its decisions on products that remain on the market without authorization.

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MANILA – The congressional bicameral conference committee on Wednesday approved a measure that would regulate the importation, manufacture, sale, packaging, distribution, use, and communication of vaporized nicotine and non-nicotine products, as well as novel tobacco products. During the conference meeting, House Deputy Speaker Rufus Rodriguez said the measure aims to offer an alternative for Filipinos who want to quit smoking.

Recto, however, noted that while Congress intends to push for the shift from smoking to vaping, the bill does not back its promotion “as a lifestyle.”

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Late last year, China amended its laws, so that vaping product manufacturers are now subject to strict regulation by the Chinese government, under the same regulatory authority as combustible cigarettes. In this episode of RegWatch, we are joined by esteemed regulatory lawyers Azim Chowdhury in Washington, D.C., and David Ettinger in Shanghai, China, both from the firm Keller & Heckman.

Could China’s new regs threaten vaping across the globe? Find out!

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Steeping in the vape world is a misleading term. Normally it’s defined as putting a solid in water to soften, or to extract flavor—like steeping tea or marinating meat. When referring to steeping e-liquid, the word takes on a slightly different meaning. A more appropriate term would be “aging” your e-juice.

Steeping e-juice involves letting it age to achieve better flavor. There are many ways to do this, which we will go into more depth later. Essentially, it means letting the e-juice sit. The most important factor in this equation is time. It allows the ingredients (PG/VG, flavorings, and nicotine) to blend together.