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Vaping for a short period of time causes immediate harmful physiological changes that can lead to chronic diseases, such as lung disease and cancer, according to a new UCLA study.

The study published Aug. 9 found that puffing on a vaping device for 30 minutes causes a measurable increase in the oxidative stress levels of nonhabitual e-cigarette or tobacco cigarette users. Oxidative stress is a well-known risk factor for heart disease, lung disease, cancer and accelerated aging, according to Dr. Holly Middlekauff, one of the authors of the study and a professor of medicine in the cardiology division at the David Geffen School of Medicine.