0
0
0
s2sdefault

Results from a study published in JAMA fail to demonstrate the noninferiority of cytisine compared with varenicline as a smoking cessation agent. Although cytisine was better tolerated by patients, varenicline was associated with greater likelihood of continuous smoking abstinence.

Prior trials have demonstrated that cytisine is more effective than placebo and nicotine replacement therapy for smoking cessation. However, its relative efficacy compared with varenicline, the most effective known smoking cessation agent, is unclear.