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An ever accumulating volume of scientific and preclinical data is suggesting that e-cigarettes are at least as harmful as regular smoking, i.e. combustible cigarettes you light up, and not a safe alternative. Understandably, most of the focus has been on the effects on the lungscardiovascular disease, and addiction. But recently, a growing body of scientific studies are starting to show the serious potential negative effects e-cigarette use may have on the brain.