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The city Health Department wants kids to beware of reefer madness.

The agency recently warned doctors about the potential dangers of youths smoking weed and other substances — less than two months after the state green-lit recreational marijuana for adults 21 and up.

In an email blasted out last week to city doctors and public health officials, DOH chief medical officer Dr. Michelle Morse described a troubling uptick in kids puffing on pot, e-cigarettes and hookah.