Dependence on tobacco and nicotine

  • Brennan, K., Crowther A., Putt F., Roper V., Waterhouse U., Truman P. Tobacco particulate matter self-administration in rats. Addiction Biology, doi:10.1111/adb.12099 [PDF]
  • Fagerstrom K. Determinants of tobacco use and renaming the FTND to the Fagerstrom Test for Cigarette Dependence. Nicotine Tob Res. 2012: 14; 75-78 [PDF]
  • Fagerstrom K & Eissenberg T. Dependence to tobacco and nicotine Products: A case for product specific assessment. Nic & Tob Res. 2012:14; 1382-1390. doi:10.1093/ntr/nts007 [PDF]

E-cig cartridges contents, refill fluids and vapour

  • Westenberger BJ. Evaluation of e-cigarettes. Rockville, MD: US FDA, Center for Drug Evaluation and Research, Division of Pharmaceutical Analysis; 2009. http://www.fda.gov/downloads/Drugs/ScienceResearch/UCM173250.pdf
  • Goniewicz ML, et al. Nicotine Levels in Electronic Cigarettes. Nicotine & Tobacco Research 2012,15:158-166.
  • Cheah NP, et al. Electronic nicotine delivery systems: regulatory and safety challenges: Singapore perspective. Tobacco Control 2012, 1:1. (about mislabeling)
  • Laugesen M: Ruyan nicotine electronic inhaler/e-cigarette: Bench-top tests. In Conference of the SRNT. Dublin (Ireland); 2009. http://www.healthnz.co.nz/DublinEcigBenchtopHandout.pdf
  • Trtchounian A, Talbot P: Electronic nicotine delivery systems: is there a need for regulation? Tob Control 2011, 20:47-52.

Source: Prof. Riccardo Polosa, Inst. of Internal Medicine, Centre for the Prevention and Cure of Tabagism, Univ. of Catania. This email address is being protected from spambots. You need JavaScript enabled to view it.

E-cigarettes clinical studies

  • Farsalinos KE, Romagna G. Chronic idiopathic neutrophilia in a smoker, relieved after smoking cessation with the use of electronic cigarette: a case report. Clin Med Insights Case Rep. 2013, 6:15-21.

E-cigarettes: second-hand exposure to vapour

  • Flouris AD, et al.: Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function. Inhal Toxicol. 2013, 25:91-101.
  • Schripp T, et al.: Does e-cigarette consumption cause passive vaping? Indoor Air 2013, 23:25-31.
  • McAuley TR, et al.: Comparison of the effects of e-cigarette vapor and cigarette smoke on indoor air quality. Inhal Toxicol 2012, 24:850-857.

Source: Prof. Riccardo Polosa, Inst. of Internal Medicine, Centre for the Prevention and Cure of Tabagism, Univ. of Catania. This email address is being protected from spambots. You need JavaScript enabled to view it.

E-cigs ability to deliver nicotine

  • Ingebrethsen BJ, Cole SK, Alderman SL: Electronic cigarette aerosol particle size distribution measurements. Inhal Toxicol 2012, 24:976-984.
  • Bullen C, et al. Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial. Tobacco Control 2010, 19:98-103
  • Vansickel AR, Eissenberg T: Electronic cigarettes: effective nicotine delivery after acute administration. Nicotine & Tobacco Research 2013, 15:267-270.
  • Williams M, Talbot P: Variability among electronic cigarettes in the pressure drop, airflow rate, and aerosol production. Nicotine & Tobacco Research 2011, 13:1276-1283.
  • Trtchounian A, Williams M, Talbot P: Conventional and electronic cigarettes (e-cigarettes) have different smoking characteristics. Nicotine & Tobacco Research 2010, 12:905-912.
  • Etter JF, Bullen C: Saliva cotinine levels in users of electronic cigarettes. European Respiratory Journal 2011, 38:1219-1220. (Letter)
  • Vansickel AR, Weaver MF, Eissenberg T: Clinical laboratory assessment of the abuse liability of an electronic cigarette. Addiction 2012, 107:1493-1500.

Source: Prof. Riccardo Polosa, Inst. of Internal Medicine, Centre for the Prevention and Cure of Tabagism, Univ. of Catania. This email address is being protected from spambots. You need JavaScript enabled to view it.This email address is being protected from spambots. You need JavaScript enabled to view it.

 

  • Farsalinos, K.E.; Romagna, G.; Tsiapras, D.; Kyrzopoulos, S.; Voudris, V. Evaluation of Electronic Cigarette Use (Vaping) Topography and Estimation of Liquid Consumption: Implications for Research Protocol Standards Definition and for Public Health Authorities’ Regulation. Int. J. Environ. Res. Public Health 2013, 10, 2500-2514.

 

E-cigs effects on user health

  • Flouris AD, et al.: Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function. Inhal Toxicol. 2013, 25:91-101.
  • Vansickel AR, et al. Clinical Laboratory Model for Evaluating the Acute Effects of Electronic “Cigarettes”: Nicotine Delivery Profile and Cardiovascular and Subjective Effects. Cancer Epidemiology Biomarkers & Prevention. 2010, 19:1945-1953.
  • Vardavas CI, et al.: Short-term pulmonary effects of using an electronic cigarette: impact on respiratory flow resistance, impedance, and exhaled nitric oxide. Chest 2012, 141:1400-1406.
  • Flouris AD, et al.: Acute effects of electronic and tobacco cigarette smoking on complete blood count. Food Chem Toxicol 2012, 50:3600-3603.
  • Miura K, et al. Safety Assessment of Electronic Cigarettes in Smokers. Seikatsu Eisei (Journal of Urban Living and Health Association) 2011;55:59-64.
  • Farsalinos, K.E.; Romagna, G.; Allifranchini, E.; Ripamonti, E.; Bocchietto, E.; Todeschi, S.; Tsiapras, D.; Kyrzopoulos, S.; Voudris, V. Comparison of the Cytotoxic Potential of Cigarette Smoke and Electronic Cigarette Vapour Extract on Cultured Myocardial Cells. Int. J. Environ. Res. Public Health 2013, 10, 5146-5162.

Source: Prof. Riccardo Polosa, Inst. of Internal Medicine, Centre for the Prevention and Cure of Tabagism, Univ. of Catania. This email address is being protected from spambots. You need JavaScript enabled to view it.

E-cigs efficacy in assisting smoking cessation

  • Bullen C, et al.: Effect of an electronic nicotine delivery device ( e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial. Tobacco Control 2010, 19:98-103
  • Vansickel AR, et al.: A Clinical Laboratory Model for Evaluating the Acute Effects of Electronic “Cigarettes”: Nicotine Delivery Profile and Cardiovascular and Subjective Effects. Cancer Epidemiology Biomarkers & Prevention 2010, 19:1945-1953.
  • Dawkins L, et al.: The electronic-cigarette: Effects on desire to smoke, withdrawal symptoms and cognition. Addictive Behaviors 2012, 37:970-973.
  • Caponnetto P, et al.: Successful smoking cessation with electronic cigarettes in smokers with a documented history of recurring relapses: a case series. BMC J Medical Case Reports 2011, 5:1-6.
  • Etter J-F, Bullen C: Electronic cigarette: users profile, utilization, satisfaction and perceived efficacy. Addiction 2011, 106:2017-2028.
  • Siegel MB, et al.: Electronic cigarettes as a smoking-cessation tool: results from an online survey. Am J Prev Med 2011, 40:472-475.

Source: Prof. Riccardo Polosa, Inst. of Internal Medicine, Centre for the Prevention and Cure of Tabagism, Univ. of Catania. This email address is being protected from spambots. You need JavaScript enabled to view it.This email address is being protected from spambots. You need JavaScript enabled to view it.

  • Caponnetto P, Campagna D, Cibella F, Morjaria JB, Caruso M, et al. (2013) EffiCiency and Safety of an eLectronic cigAreTte (ECLAT) as Tobacco Cigarettes Substitute: A Prospective 12-Month Randomized Control Design Study. PLoS ONE 8(6): e66317. doi:10.1371/journal.pone.0066317

E-cigs potential as a gateway to tobacco use

  • Cho JH, et al.: Electronic-cigarette smoking experience among adolescents. J Adolesc Health 2011, 49:542-546.
  • Choi K, et al.: Young Adults’ Favorable Perceptions of Snus, Dissolvable Tobacco Products, and Electronic Cigarettes: Findings From a Focus Group Study. American Journal of Public Health 2012:e1-e6
  • Choi K, Forster J: Characteristics Associated With Awareness, Perceptions, and Use of Electronic Nicotine Delivery Systems Among Young US Midwestern Adults. American Journal of Public Health 2013, 17:17.
  • Pepper JK, et al.: Adolescent males' awareness of and willingness to try electronic cigarettes. J Adolesc Health 2013, 52:144-150.
  • Goniewicz ML, Zielinska-Danch W: Electronic cigarette use among teenagers and young adults in Poland. Pediatrics 2012, 130:2011-3448.
  • Grana RA: Electronic cigarettes: a new nicotine gateway? J Adolesc Health. 2013, 52:135-6. doi: 10.1016/j.jadohealth.2012.11.007.

Source: Prof. Riccardo Polosa, Inst. of Internal Medicine, Centre for the Prevention and Cure of Tabagism, Univ. of Catania. This email address is being protected from spambots. You need JavaScript enabled to view it.

E-cigs users experiences

  • Dawkins, L., Turner, J., Roberts, A. and Soar, K. (2013), ‘Vaping’ profiles and preferences: an online survey of electronic cigarette users. Addiction, 108: 1115–1125. doi: 10.1111/add.12150
  • Deepa R. Camenga, Jennifer Delmerico, Grace Kong, Dana Cavallo, Andrew Hyland, K. Michael Cummings, Suchitra Krishnan-Sarin, Trends in Use of Electronic Nicotine Delivery Systems by Adolescents, Addictive Behaviors, Available online 17 September 2013, ISSN 0306-4603, http://dx.doi.org/10.1016/j.addbeh.2013.09.014.

Efficacy in reducing tobacco withdrawal symptoms

  • Bullen C, et al.: Effect of an electronic nicotine delivery device ( e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial. Tobacco Control 2010, 19:98-103
  • Eissenberg T: Electronic nicotine delivery devices: ineffective nicotine delivery and craving suppression after acute administration. Tobacco Control 2010, 19:87-88. (Letter)
  • Vansickel AR, et al.: A Clinical Laboratory Model for Evaluating the Acute Effects of Electronic “Cigarettes”: Nicotine Delivery Profile and Cardiovascular and Subjective Effects. Cancer Epidemiology Biomarkers & Prevention 2010, 19:1945-1953.
  • Dawkins L, et al: The electronic-cigarette: Effects on desire to smoke, withdrawal symptoms and cognition. Addictive Behaviors 2012, 37:970-973.
  • Vansickel AR, Eissenberg T: Electronic cigarettes: effective nicotine delivery after acute administration. Nicotine & Tobacco Research 2013, 15:267-270.

Source: Prof. Riccardo Polosa, Inst. of Internal Medicine, Centre for the Prevention and Cure of Tabagism, Univ. of Catania. This email address is being protected from spambots. You need JavaScript enabled to view it.

Electronic Cigarettes Harm Reduction

  • Etter J-F, Bullen C: Electronic cigarette: users profile, utilization, satisfaction and perceived efficacy. Addiction 2011, 106:2017-2028.
  • Foulds J, Veldheer S: Commentary on Etter & Bullen (2011): Could E-cigs become the ultimate nicotine maintenance device? Addiction 2011, 106:2029-2030.
  • Kralikova EVA, et al.: The electronic cigarette: What proportion of smokers have tried it and how many use it regularly? Addiction 2012, 107:1528-1529 (Letter)
  • Cahn, Z., Siegel, M., 2010. Electronic cigarettes as a harm reduction strategy for tobacco control: A step forward or a repeat of past mistakes? Journal of Public Health Policy 32, 16–31.

Source: Prof. Riccardo Polosa, Inst. of Internal Medicine, Centre for the Prevention and Cure of Tabagism, Univ. of Catania. This email address is being protected from spambots. You need JavaScript enabled to view it.

Snus

  • Lee, P. Epidemiological evidence relating snus to health - an updated review based on recent publications. Harm Reduction Journal, doi:10.1186/1477-7517-10-36 [URL]

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