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The wires this week were not so much humming as soaring in full operatic splendour over the vexed subject of whether addiction is a brain disease (hereafter BDMA or Brain Disease Model of Addiction).  It was sparked by a very interesting development in the addictions field, akin to the split among academics, clinicians and public health officials over safer nicotine products.

A fissure has opened between those who subscribe to the BDMA and those who believe that the phenomenon of addiction is far more complex than such a reductionist conclusion allows.  While the American psychologist Stanton Peele has been challenging the BDMA for years, he has often been a lone figure in an addictions landscape where the BDMA has become the orthodoxy, promoted vigorously by the multi-million-dollar US addictions industry and by such august bodies as the US National Institute on Drug Abuse, a federal agency which funds more addiction research than any other institution on the planet.

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An economic forecasting company has estimated that if smoking in the UK declines at the current rate, nobody will be smoking by around 2050. Frontier Economics predicts that:

1. Our central forecast is for the Government to meet its smoke-free target – to reduce smoking prevalence to 5% or below of England’s adult population – around 2040. This forecast is based on a continuation of current above-inflation excise increases and known regulatory interventions.

2.  If smoking then continued to decline at the same rate after 2040, it would reach 0% in around 2051.

3. Smoking is in long-run decline, but since 2012 it has declined at more than twice the rate seen between 1993 and 2011. Smokers switching to e-cigarettes appear to have made a material contribution to that recent trend.

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My friend Ethan Nadelmann once told of a conversation he had with an officer from the US Drug Enforcement Administration. Ethan asked him if there was anything they could agree upon, any common ground across which a bridge could be built. The officer replied that the wall between their views was just too high for him to want to climb over and engage in meaningful dialogue.

On the strength of the latest example hot from the desk of the WHO, I fear that is where we are with this agency too. It almost seems pointless to continue berating the WHO over its intransigent opposition to safer nicotine products (SNP). At one level it is a bit like continually criticising the DEA for not supporting drug law reform. Except the DEA is a law enforcement agency; they have a remit to enforce the drug laws whatever they might be. They don’t have a mission to be concerned about the welfare of drug users – and they aren’t. But the WHO is supposed to be an agency with a ‘health for all’ remit, so the deliberate undermining of efforts to increase the availability of SNP is something that should be highlighted at every turn.

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Insightful read of the week award goes to a review of a new book on the AIDS pandemic in which the authors reveal how the leadership of the WHO failed miserably to save thousands of lives until redeemed by an administrator, Dr Jonathan Mann who did everything right from inaugurating World AIDS day to involving NGOs and fighting stigma and discrimination. Yet he felt he had to resign from WHO, frustrated that his boss was just putting every obstacle in his path. Mann tragically died in an air crash in 1998.

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In May, the Icelandic pro-vaping coalition Veipum Lifum (VL) held a conference in Reykjavik. On their website, they included a link to the WHO FCTC as well as links to the Icelandic Parliament and an article in Icelandic media both of which also carried the WHO logo. On 18th August VL  received a letter from the legal unit of the WHO Regional Office for Europe threatening legal action stating that they had not given permission for the logo to be used especially as placing it on the VL website suggested that the WHO endorsed the use of e-cigarettes. The WHO demanded that the logo be removed not only from the VL website, but also from the other locations over which of course, VL had no control. The letter also said that examples of ‘misuse’ of the logo were attached which they were not.

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Cigarette smoking continues its rapid decline in Japan while the upward trajectory of smokers seeking alternative nicotine products shows no signs of slowing down. According to PMI a small percentage (calculated variously at between 5—15%) of their IQOS customers are dual users, but the rest have fully converted. The access to the market for companies like PMI afforded by the Japanese government plays a big part in this; advertising is seemingly allowed in any ways the imagination can conceive and is just as ubiquitous as the most aggressive cigarette advertising. Tobacco regulators around the world may choke on the vapour here, but the experience in Japan strongly suggests that putting obstacles in the way of e-cigarette and HNB marketing simply prolongs your cigarette problem.

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The heat and dust continues to swirl around the Foundation for a Smoke Free World https://www.smoke-freeworld.org/leadership.

Whether the negativity continues will very much depend on what it actually does, although suspicion will always dog its tracks no doubt. The WHO have weighed in with a statement urging all governments and public health bodies to steer clear and refuse any collaboration: https://www.cnbc.com/2017/09/28/who-tells-governments-to-reject-philip-morris-funded-smoking-foundation.html

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As you can see, this is blog number 33 and so I hope I am not repeating this little anecdote, even though it does bear repeating.

There used to be a BBC TV political comedy called Yes Minister in which the senior civil servant Sir Humphrey Appleby was consistently trying to derail any initiative by his Minister Jim Hacker, which might not be in the interests of the civil service. One failsafe tactic, should the Minister suddenly announce such a move, would be for Sir Humphrey to say, ‘That’s a very brave decision, Minister’ At which point Hacker would turn pale and instantly drop the idea. Because no politician who is actually in power wants to be regarded as ‘brave’ as that invariably means a risky enterprise which could end in the sack, reshuffled to some low-level post, a loss of votes or even the loss of a parliamentary seat entirely.

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Harry Shapiro Director DrugWise

No guesses as to the big story of the moment – the announcement that PMI are funding a Foundation for a Smoke-Free World to the tune of $80 million annually over the next twelve years. The interim president is Dr Derek Yach, former WHO director for noncommunicable diseases and mental health where he led the development of the Framework Convention on Tobacco Control. Eyebrows have shot skywards at this appointment leading to inevitable claims that Dr Yach has been won over to the Dark Side.

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Harry Shapiro Director DrugWise

There is a new Holy Grail within the world of tobacco control – the reduced nicotine cigarette which proponents claim will make cigarettes so unattractive that smoking tobacco will be eliminated. This was the thrust of a recent commentary from Scott Gottlieb and Mitch Zeller in the New England Journal of Medicine http://www.nejm.org/doi/full/10.1056/NEJMp1707409#t=article and is likely to become a major tobacco control policy goal internationally. Scientific evidence is being presented that this works; the Gottlieb commentary cited the FDA-funded study by Eric Donny which has been challenged by Dr Brad Rodhu. No doubt ‘methodologies at dawn’ will be played out in the medical press in the coming months.

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Harry Shapiro Director DrugWise

Two contrasting items this week about the idea that celebrities who are either seen to be endorsing drug use or actively campaigning against it, have any influence on decision-making among young people.

The first is an opinion piece by Guy Bentley in the Washington Examiner about the continuing controversy over movie stars smoking on-screen. It was prompted by this report, which showed the use or implied use of tobacco in top-grossing movies rose 72 percent from 2010 to 2016. In PG-13 movies these "tobacco incidents" rose 43 percent, and there was a 90 percent increase for R-rated movies. The researchers included e-cigarettes in their category of tobacco incidents, despite the total lack of tobacco in an e-cigarette. It will therefore come as no shock that one of the authors of this report was one S. Glantz and Bentley goes on to describe why this kind of causal relationship research is deeply flawed.